Basic Information
ID: ALA4347307
Type: Binding
Description: Irreversible desensitizing activity at human TRPA1 expressed in HEK293 cells assessed as CA-induced increase in Ca2+ influx at >30 uM pretreated with compound followed by drug wash-out and CA challenge by Fluo-4-AM dye based fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Transient receptor potential cation channel subfamily A member 1(ALA6007)
Document: ALA4346663
Irreversible desensitizing activity at human TRPA1 expressed in HEK293 cells assessed as CA-induced increase in Ca2+ influx at >30 uM pretreated with compound followed by drug wash-out and CA challenge by Fluo-4-AM dye based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4347307
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.18 | 3.80 | 3.80 |
| 301.73 | 3.69 | 3.69 |
| 301.73 | 3.69 | 3.69 |
| 285.27 | 3.18 | 3.18 |