Basic Information
ID: ALA4347598
Type: Binding
Description: Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Histone deacetylase(ALA2093865)
Document: ALA4346670
Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4347598
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 401.39 | 2.93 | 2.93 |
| 413.46 | 3.76 | 3.76 |
| 429.91 | 4.27 | 4.27 |
| 367.84 | 2.57 | 2.57 |
| 459.94 | 4.28 | 4.28 |
| 450.33 | 4.53 | 4.53 |
| 393.88 | 3.10 | 3.10 |
| 395.90 | 3.35 | 3.35 |
| 464.36 | 4.92 | 4.92 |
| 447.90 | 4.41 | 4.41 |
| 450.33 | 4.53 | 4.53 |
| 464.36 | 4.92 | 4.92 |
| 431.45 | 3.89 | 3.89 |
| 479.90 | 4.52 | 4.52 |
| 405.82 | 3.24 | 3.24 |
| 423.91 | 2.36 | 2.36 |
| 450.33 | 4.53 | 4.53 |
| 421.93 | 3.52 | 3.52 |
| 453.87 | 4.12 | 4.12 |
| 433.88 | 4.02 | 4.02 |
| 419.85 | 3.63 | 3.63 |
| 353.81 | 2.18 | 2.18 |
| 464.36 | 4.92 | 4.92 |
| 481.45 | 4.77 | 4.77 |
| 461.93 | 4.80 | 4.80 |
| 391.79 | 2.85 | 2.85 |