Basic Information
ID: ALA4347606
Type: Binding
Description: Inhibition of HDAC8 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Histone deacetylase 8(ALA3192)
Document: ALA4346670
Inhibition of HDAC8 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4347606
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 367.84 | 2.57 | 2.57 |
| 464.36 | 4.92 | 4.92 |
| 450.33 | 4.53 | 4.53 |
| 479.90 | 4.52 | 4.52 |
| 453.87 | 4.12 | 4.12 |
| 419.85 | 3.63 | 3.63 |
| 461.93 | 4.80 | 4.80 |