Basic Information
ID: ALA4347974
Type: ADME
Description: Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition by ELISA
Format: BAO_0000357
Organism: Homo sapiens
Target: Cyclooxygenase-1(ALA221)
Document: ALA4346673
Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4347974
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 381.38 | 3.51 | 3.51 |
| 214.27 | 2.27 | 2.27 |
| 212.25 | 2.25 | 2.25 |
| 324.36 | 4.03 | 4.03 |
| 228.25 | 1.95 | 1.95 |
| 322.34 | 3.55 | 3.55 |
| 304.35 | 3.41 | 3.41 |
| 230.27 | 1.97 | 1.97 |
| 201.23 | 1.36 | 1.36 |
| 308.36 | 4.33 | 4.33 |
| 306.37 | 3.89 | 3.89 |
| 306.34 | 3.85 | 3.85 |