Assay Report Card

Basic Information

ID: ALA4348278

Type: Functional

Description: Induction of apoptosis in human HCT116 cells expressing wild type p53 assessed as decrease in cdc2 expression level at 4 times antiproliferative IC50 incubated for 24 hrs by Western blot analysis relative to control

Organism: Homo sapiens

Cell type: HCT-116

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
444.394.574.57
444.493.683.68
343.432.252.25
427.542.802.80
471.424.234.23