Basic Information
ID: ALA4348280
Type: Functional
Description: Induction of apoptosis in human HCT116 cells expressing wild type p53 assessed as decrease in cyclin D1 expression level at 4 times antiproliferative IC50 incubated for 24 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: HCT-116
Activity Charts
Bioactivity
Activity Types for Assay ALA4348280
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.50 | 4.28 | 4.28 |
| 420.50 | 3.17 | 3.17 |
| 444.39 | 4.57 | 4.57 |
| 444.49 | 3.68 | 3.68 |
| 343.43 | 2.25 | 2.25 |
| 427.54 | 2.80 | 2.80 |
| 370.44 | 2.02 | 2.02 |
| 471.42 | 4.23 | 4.23 |