Basic Information
ID: ALA4348491
Type: Binding
Description: Inhibition of N-terminal GST-tagged human ALK L1196M mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus expression system using srctide as substrate incubated for 1 hr by mobility shift assay
Format: BAO_0000019
Organism: Homo sapiens
Target: ALK tyrosine kinase receptor(ALA4247)
Document: ALA4346688
Inhibition of N-terminal GST-tagged human ALK L1196M mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus expression system using srctide as substrate incubated for 1 hr by mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4348491
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.35 | 5.04 | 5.04 |
| 558.15 | 6.36 | 6.36 |
| 657.20 | 3.82 | 3.82 |
| 656.16 | 4.24 | 4.24 |
| 517.01 | 4.34 | 4.34 |
| 574.11 | 4.40 | 4.40 |
| 588.13 | 4.61 | 4.61 |
| 602.12 | 4.14 | 4.14 |
| 574.06 | 3.54 | 3.54 |