Basic Information
ID: ALA4348493
Type: Binding
Description: Potency index, ratio of IC50 for ceritinib to IC50 for test compound for inhibition of N-terminal GST-tagged human ALK G1202R mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus expression system using srctide as substrate incubated for 1 hr by mobility shift assay
Format: BAO_0000019
Organism: Homo sapiens
Target: ALK tyrosine kinase receptor(ALA4247)
Document: ALA4346688
Potency index, ratio of IC50 for ceritinib to IC50 for test compound for inhibition of N-terminal GST-tagged human ALK G1202R mutant cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus expression system using srctide as substrate incubated for 1 hr by mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4348493
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 588.13 | 4.61 | 4.61 |