Basic Information
ID: ALA4348706
Type: Binding
Description: Inhibition of human topoisomerase 1 at 200 uM using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase I(ALA1781)
Document: ALA4346697
Inhibition of human topoisomerase 1 at 200 uM using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4348706
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.50 | 3.09 | 3.09 |
| 475.52 | 4.19 | 4.19 |
| 421.40 | 4.70 | 4.70 |
| 478.48 | 2.68 | 2.68 |
| 445.49 | 4.19 | 4.19 |
| 445.49 | 4.27 | 4.27 |
| 515.54 | 3.87 | 3.87 |
| 475.52 | 3.12 | 3.12 |
| 491.52 | 2.87 | 2.87 |
| 502.54 | 4.38 | 4.38 |
| 464.46 | 2.12 | 2.12 |
| 461.49 | 3.93 | 3.93 |
| 503.57 | 4.97 | 4.97 |