Basic Information
ID: ALA4348787
Type: Binding
Description: Inhibition of human recombinant GST-tagged SHP2 (catalytic domain 1116 to 2162 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetric analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Protein-tyrosine phosphatase 2C(ALA3864)
Document: ALA4346701
Inhibition of human recombinant GST-tagged SHP2 (catalytic domain 1116 to 2162 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4348787
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.23 | 7.23 |
| 183.91 | ||
| 582.68 | 6.94 | 6.94 |
| 633.58 | 8.10 | 8.10 |
| 643.58 | 7.56 | 7.56 |
| 578.72 | 7.11 | 7.11 |