Basic Information
ID: ALA4348832
Type: Binding
Description: Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated for 20 mins followed by anti-IgM antibody stimulation and measured after 30 mins by alphascreen assay
Organism: Homo sapiens
Cell type: Ramos
Activity Charts
Bioactivity
Activity Types for Assay ALA4348832
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 453.53 | 2.88 | 2.88 |
| 394.48 | 1.98 | 1.98 |
| 437.55 | 2.37 | 2.37 |
| 382.47 | 1.98 | 1.98 |
| 382.47 | 1.98 | 1.98 |
| 458.53 | 2.43 | 2.43 |
| 438.54 | 1.99 | 1.99 |
| 412.50 | 1.60 | 1.60 |
| 455.59 | 2.67 | 2.67 |
| 395.47 | 1.94 | 1.94 |
| 396.50 | 2.37 | 2.37 |
| 424.51 | 1.60 | 1.60 |
| 368.49 | 2.45 | 2.45 |
| 368.45 | 1.59 | 1.59 |
| 396.50 | 2.22 | 2.22 |
| 439.52 | 1.96 | 1.96 |
| 438.54 | 1.99 | 1.99 |
| 440.55 | 2.38 | 2.38 |
| 398.47 | 1.21 | 1.21 |
| 396.50 | 2.22 | 2.22 |
| 370.46 | 1.83 | 1.83 |