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Protac activity against VHL/RIPK2 in human THP-1 cells assessed as induction of RIPK2 protein degradation at 10 nM relative to control

Basic Information

ID: ALA4349406

Type: Binding

Description: Protac activity against VHL/RIPK2 in human THP-1 cells assessed as induction of RIPK2 protein degradation at 10 nM relative to control

Format: BAO_0000219

Organism: Homo sapiens

Cell type: THP-1

Target:  von Hippel-Lindau disease tumor suppressor/Receptor-interacting serine/threonine-protein kinase 2(ALA4296139)

Document:  ALA4346721

Protac activity against VHL/RIPK2 in human THP-1 cells assessed as induction of RIPK2 protein degradation at 10 nM relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1060.33