Basic Information
ID: ALA4349936
Type: Binding
Description: Inverse agonist activity at RORgammat in mouse splenocytes derived naive T cells assessed as suppression of T cell differentiation to Th17 cells by measuring IL-17 secretion in presence of anti-CD4/anti-IFNgamma/TGFbeta/IL-6 for 6 days by ELISA
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4349936
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.24 | 5.40 | 5.40 |
| 410.26 | 5.87 | 5.87 |
| 411.24 | 5.26 | 5.26 |
| 428.25 | 6.01 | 6.01 |