Basic Information
ID: ALA4350023
Type: ADME
Description: Metabolic stability in human liver microsomes assessed as parent compound remaining at 1 uM preincubated for 5 mins followed by NADPH addition after 30 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4350023
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.37 | 6.53 | 6.53 |
| 429.23 | 5.40 | 5.40 |
| 428.25 | 6.01 | 6.01 |
| 444.70 | 6.52 | 6.52 |
| 428.25 | 6.01 | 6.01 |
| 375.81 | 5.21 | 5.21 |
| 411.24 | 5.26 | 5.26 |
| 425.82 | 5.80 | 5.80 |
| 428.25 | 6.01 | 6.01 |
| 411.79 | 5.49 | 5.49 |
| 446.24 | 6.14 | 6.14 |
| 426.26 | 5.57 | 5.57 |
| 410.26 | 5.87 | 5.87 |
| 446.24 | 6.14 | 6.14 |
| 444.70 | 6.52 | 6.52 |
| 444.70 | 6.52 | 6.52 |
| 411.24 | 5.26 | 5.26 |
| 478.25 | 6.89 | 6.89 |
| 407.83 | 5.66 | 5.66 |
| 424.28 | 6.17 | 6.17 |
| 411.24 | 5.26 | 5.26 |
| 393.80 | 5.35 | 5.35 |
| 389.84 | 5.52 | 5.52 |
| 444.80 | 5.63 | 5.63 |
| 443.81 | 6.23 | 6.23 |
| 424.28 | 6.17 | 6.17 |
| 428.25 | 6.01 | 6.01 |
| 479.15 | 7.17 | 7.17 |
| 440.28 | 5.88 | 5.88 |
| 407.83 | 5.66 | 5.66 |
| 462.79 | 5.77 | 5.77 |
| 407.83 | 5.66 | 5.66 |
| 446.24 | 6.14 | 6.14 |
| 461.80 | 6.37 | 6.37 |
| 428.25 | 6.01 | 6.01 |
| 478.25 | 6.89 | 6.89 |
| 377.35 | 4.84 | 4.84 |
| 461.80 | 6.37 | 6.37 |
| 479.79 | 6.51 | 6.51 |
| 428.25 | 6.01 | 6.01 |
| 407.83 | 5.66 | 5.66 |
| 446.24 | 6.14 | 6.14 |
| 424.28 | 6.17 | 6.17 |
| 408.82 | 5.06 | 5.06 |