Basic Information
ID: ALA4350183
Type: Binding
Description: Substrate activity at human NTCP expressed in HEK293 cells harboring pEGFP assessed as V max/Km for transporter-mediated drug uptake measured for 30 mins in presence of sodium chloride by UPLC-MS/MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Bile acid transporter(ALA5287)
Document: ALA4346741
Substrate activity at human NTCP expressed in HEK293 cells harboring pEGFP assessed as V max/Km for transporter-mediated drug uptake measured for 30 mins in presence of sodium chloride by UPLC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4350183
Vmax/Km
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.48 | 2.70 | 2.70 |
| 515.71 | 2.37 | 2.37 |
| 863.05 | 5.87 | 5.87 |
| 877.07 | 6.26 | 6.26 |
| 877.07 | 6.26 | 6.26 |
| 834.99 | 5.23 | 5.23 |