Basic Information
ID: ALA4350262
Type: Binding
Description: Inhibition of Trypanosoma brucei PDEB1 catalytic domain (565 to 918 residues) expressed in Escherichia coli BL21 incubated for 20 mins using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit based luminometry
Organism: Trypanosoma brucei
Activity Charts
Bioactivity
Activity Types for Assay ALA4350262
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.56 | 3.11 | 3.11 |
| 528.65 | 4.43 | 4.43 |
| 541.69 | 5.82 | 5.82 |
| 443.55 | 4.93 | 4.93 |
| 376.50 | 4.53 | 4.53 |
| 479.65 | 5.49 | 5.49 |
| 503.62 | 5.48 | 5.48 |
| 499.61 | 4.81 | 4.81 |
| 419.53 | 3.38 | 3.38 |
| 489.62 | 3.76 | 3.76 |
| 542.68 | 4.74 | 4.74 |
| 476.58 | 2.50 | 2.50 |
| 423.54 | 4.06 | 4.06 |
| 475.63 | 4.81 | 4.81 |
| 477.61 | 3.66 | 3.66 |
| 481.62 | 4.34 | 4.34 |
| 452.60 | 3.58 | 3.58 |
| 480.59 | 3.18 | 3.18 |
| 483.61 | 5.46 | 5.46 |
| 396.49 | 2.15 | 2.15 |
| 558.68 | 4.44 | 4.44 |
| 453.54 | 1.27 | 1.27 |
| 540.66 | 4.65 | 4.65 |
| 546.64 | 4.57 | 4.57 |
| 546.64 | 4.57 | 4.57 |
| 558.68 | 4.44 | 4.44 |
| 476.58 | 3.58 | 3.58 |
| 542.68 | 4.74 | 4.74 |