ID: ALA4350283
Type: Binding
Description: Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as reduction in conversion of SAH to AMP using histone H3 as substrate and SAH as cosubstrate incubated for 30 mins by AMP Glo detection assay
Organism: Homo sapiens
Cell type: Sf9
Bioactivity
Activity Types for Assay ALA4350283
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
485.68 | 2.62 | 2.62 |
509.74 | 5.84 | 5.84 |
329.44 | 2.98 | 2.98 |
463.67 | 4.88 | 4.88 |
498.68 | 1.58 | 1.58 |
495.72 | 3.49 | 3.49 |
461.61 | 3.35 | 3.35 |
427.61 | 4.99 | 4.99 |
439.65 | 4.86 | 4.86 |
499.66 | 1.76 | 1.76 |
441.62 | 2.18 | 2.18 |
495.72 | 3.36 | 3.36 |
426.61 | 3.24 | 3.24 |
384.53 | 2.29 | 2.29 |
467.66 | 3.10 | 3.10 |
498.68 | 1.76 | 1.76 |
496.66 | 1.33 | 1.33 |
479.63 | 1.77 | 1.77 |
480.70 | 4.72 | 4.72 |
509.70 | 2.84 | 2.84 |
469.68 | 2.78 | 2.78 |
499.70 | 2.14 | 2.14 |
495.72 | 3.31 | 3.31 |
552.77 | 2.89 | 2.89 |
489.67 | 3.47 | 3.47 |
437.59 | 1.60 | 1.60 |
461.61 | 3.35 | 3.35 |
451.62 | 1.99 | 1.99 |
495.67 | 1.56 | 1.56 |
470.62 | 1.57 | 1.57 |
507.72 | 5.53 | 5.53 |
477.70 | 5.27 | 5.27 |
427.55 | 1.39 | 1.39 |
435.62 | 4.28 | 4.28 |
485.64 | 3.08 | 3.08 |
461.61 | 3.35 | 3.35 |
483.66 | 2.36 | 2.36 |
470.62 | 0.97 | 0.97 |
505.67 | 2.26 | 2.26 |
472.12 | 6.11 | 6.11 |
495.72 | 3.22 | 3.22 |
509.74 | 5.24 | 5.24 |
468.69 | 4.94 | 4.94 |
455.67 | 5.60 | 5.60 |
503.69 | 4.94 | 4.94 |
423.58 | 4.41 | 4.41 |
412.58 | 2.85 | 2.85 |
498.68 | 2.35 | 2.35 |
467.70 | 5.47 | 5.47 |
468.67 | 4.85 | 4.85 |
467.66 | 2.75 | 2.75 |
465.69 | 5.44 | 5.44 |
465.65 | 2.20 | 2.20 |
451.62 | 1.86 | 1.86 |
484.65 | 1.37 | 1.37 |
460.63 | 3.95 | 3.95 |
481.73 | 5.86 | 5.86 |
498.68 | 2.18 | 2.18 |
491.68 | 2.73 | 2.73 |