Basic Information
ID: ALA4350284
Type: Binding
Description: Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as reduction in conversion of SAH to AMP using histone H3 as substrate and SAH as cosubstrate incubated for 30 mins by AMP Glo detection assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4350284
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 485.68 | 2.62 | 2.62 |
| 509.74 | 5.84 | 5.84 |
| 329.44 | 2.98 | 2.98 |
| 463.67 | 4.88 | 4.88 |
| 498.68 | 1.58 | 1.58 |
| 495.72 | 3.49 | 3.49 |
| 461.61 | 3.35 | 3.35 |
| 427.61 | 4.99 | 4.99 |
| 439.65 | 4.86 | 4.86 |
| 499.66 | 1.76 | 1.76 |
| 441.62 | 2.18 | 2.18 |
| 495.72 | 3.36 | 3.36 |
| 426.61 | 3.24 | 3.24 |
| 384.53 | 2.29 | 2.29 |
| 467.66 | 3.10 | 3.10 |
| 498.68 | 1.76 | 1.76 |
| 496.66 | 1.33 | 1.33 |
| 479.63 | 1.77 | 1.77 |
| 480.70 | 4.72 | 4.72 |
| 509.70 | 2.84 | 2.84 |
| 469.68 | 2.78 | 2.78 |
| 499.70 | 2.14 | 2.14 |
| 495.72 | 3.31 | 3.31 |
| 552.77 | 2.89 | 2.89 |
| 489.67 | 3.47 | 3.47 |
| 437.59 | 1.60 | 1.60 |
| 461.61 | 3.35 | 3.35 |
| 451.62 | 1.99 | 1.99 |
| 495.67 | 1.56 | 1.56 |
| 470.62 | 1.57 | 1.57 |
| 507.72 | 5.53 | 5.53 |
| 477.70 | 5.27 | 5.27 |
| 427.55 | 1.39 | 1.39 |
| 435.62 | 4.28 | 4.28 |
| 485.64 | 3.08 | 3.08 |
| 461.61 | 3.35 | 3.35 |
| 483.66 | 2.36 | 2.36 |
| 470.62 | 0.97 | 0.97 |
| 505.67 | 2.26 | 2.26 |
| 472.12 | 6.11 | 6.11 |
| 495.72 | 3.22 | 3.22 |
| 509.74 | 5.24 | 5.24 |
| 468.69 | 4.94 | 4.94 |
| 455.67 | 5.60 | 5.60 |
| 503.69 | 4.94 | 4.94 |
| 423.58 | 4.41 | 4.41 |
| 412.58 | 2.85 | 2.85 |
| 498.68 | 2.35 | 2.35 |
| 467.70 | 5.47 | 5.47 |
| 468.67 | 4.85 | 4.85 |
| 467.66 | 2.75 | 2.75 |
| 465.69 | 5.44 | 5.44 |
| 465.65 | 2.20 | 2.20 |
| 451.62 | 1.86 | 1.86 |
| 484.65 | 1.37 | 1.37 |
| 460.63 | 3.95 | 3.95 |
| 481.73 | 5.86 | 5.86 |
| 498.68 | 2.18 | 2.18 |
| 491.68 | 2.73 | 2.73 |