Assay Report Card

Basic Information

ID: ALA4350327

Type: Functional

Description: Negative allosteric modulation of rat mGlu3R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobilization preincubated for 2.5 mins followed by glutamate addition by S3 Fluo-4-AM dye based fluorescence assay

Organism: Rattus norvegicus

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
339.373.823.82