Basic Information
ID: ALA4350329
Type: Binding
Description: Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Metabotropic glutamate receptor 3(ALA3067)
Document: ALA4346754
Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4350329
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.37 | 3.82 | 3.82 |
| 347.41 | 3.92 | 3.92 |
| 351.38 | 3.75 | 3.75 |
| 353.39 | 4.07 | 4.07 |
| 355.82 | 4.34 | 4.34 |
| 335.40 | 3.99 | 3.99 |
| 335.40 | 3.99 | 3.99 |
| 401.44 | 5.18 | 5.18 |
| 369.85 | 4.58 | 4.58 |
| 349.43 | 4.24 | 4.24 |
| 369.85 | 4.58 | 4.58 |
| 339.37 | 3.82 | 3.82 |
| 355.82 | 4.34 | 4.34 |
| 397.47 | 5.35 | 5.35 |
| 349.43 | 4.24 | 4.24 |
| 335.40 | 3.99 | 3.99 |
| 339.37 | 3.82 | 3.82 |
| 351.40 | 3.69 | 3.69 |
| 349.43 | 4.24 | 4.24 |