Basic Information
ID: ALA4350350
Type: Binding
Description: Inhibition of human recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate preincubated for 20 mins followed by substrate addition and incubated for 60 sec by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4350350
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.56 | 5.99 | 5.99 |
| 498.67 | 7.50 | 7.50 |
| 493.00 | 6.34 | 6.34 |
| 494.99 | 6.78 | 6.78 |
| 510.56 | 7.01 | 7.01 |
| 491.03 | 7.20 | 7.20 |
| 477.00 | 6.64 | 6.64 |
| 489.02 | 6.81 | 6.81 |
| 477.00 | 6.64 | 6.64 |
| 491.03 | 7.20 | 7.20 |
| 478.98 | 6.09 | 6.09 |
| 507.03 | 6.65 | 6.65 |
| 477.99 | 6.04 | 6.04 |
| 477.99 | 6.04 | 6.04 |
| 494.99 | 6.78 | 6.78 |
| 494.99 | 6.78 | 6.78 |
| 462.98 | 6.33 | 6.33 |
| 491.03 | 7.20 | 7.20 |
| 477.00 | 6.64 | 6.64 |
| 442.56 | 5.99 | 5.99 |
| 492.02 | 6.14 | 6.14 |
| 526.72 | 8.14 | 8.14 |
| 476.02 | 7.25 | 7.25 |
| 506.00 | 4.93 | 4.93 |
| 456.59 | 6.30 | 6.30 |
| 491.03 | 6.66 | 6.66 |
| 510.56 | 7.01 | 7.01 |
| 478.98 | 6.09 | 6.09 |
| 456.59 | 6.30 | 6.30 |
| 456.59 | 6.30 | 6.30 |
| 478.98 | 5.49 | 5.49 |
| 513.02 | 4.49 | 4.49 |
| 546.97 | 7.23 | 7.23 |
| 498.67 | 7.19 | 7.19 |
| 477.00 | 6.64 | 6.64 |
| 462.98 | 6.25 | 6.25 |
| 442.56 | 5.99 | 5.99 |
| 464.99 | 6.50 | 6.50 |
| 441.57 | 6.59 | 6.59 |
| 462.98 | 6.33 | 6.33 |
| 491.03 | 7.20 | 7.20 |
| 494.99 | 6.78 | 6.78 |
| 476.02 | 6.04 | 6.04 |
| 484.98 | 6.50 | 6.50 |
| 462.98 | 6.33 | 6.33 |
| 460.55 | 6.13 | 6.13 |
| 491.03 | 7.20 | 7.20 |
| 442.56 | 5.99 | 5.99 |
| 477.00 | 6.39 | 6.39 |
| 530.97 | 7.35 | 7.35 |
| 422.91 | 5.47 | 5.47 |
| 511.45 | 7.29 | 7.29 |
| 491.03 | 6.95 | 6.95 |
| 491.03 | 6.89 | 6.89 |
| 456.59 | 6.30 | 6.30 |
| 501.03 | 5.92 | 5.92 |