Basic Information
ID: ALA4350894
Type: Binding
Description: Selectivity index, ratio of Ki for displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from human dopamine D3 receptor expressed in HEK293 cells to Ki for displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from human dopamine D2L receptor expressed in HEK293 cells
Format: BAO_0000219
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4346764
Selectivity index, ratio of Ki for displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from human dopamine D3 receptor expressed in HEK293 cells to Ki for displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from human dopamine D2L receptor expressed in HEK293 cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4350894
Ratio Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.60 | 4.62 | 4.62 |
| 488.48 | 6.05 | 6.05 |
| 444.60 | 4.62 | 4.62 |
| 433.62 | 5.06 | 5.06 |
| 454.04 | 5.40 | 5.40 |
| 454.04 | 5.40 | 5.40 |
| 454.04 | 5.40 | 5.40 |
| 435.59 | 4.45 | 4.45 |
| 487.59 | 5.77 | 5.77 |
| 487.59 | 5.77 | 5.77 |
| 488.48 | 6.05 | 6.05 |
| 433.62 | 5.06 | 5.06 |
| 435.59 | 4.45 | 4.45 |
| 449.62 | 4.76 | 4.76 |
| 449.62 | 4.76 | 4.76 |
| 444.60 | 4.62 | 4.62 |
| 449.62 | 4.76 | 4.76 |
| 435.59 | 4.45 | 4.45 |
| 488.48 | 6.05 | 6.05 |
| 419.59 | 4.75 | 4.75 |
| 433.62 | 5.06 | 5.06 |
| 487.59 | 5.77 | 5.77 |