Basic Information
ID: ALA4351181
Type: Binding
Description: Reversal of ABCC1 (unknown origin)-mediated multidrug resistance in MDCK2 cells co-expressing MRP1 (unknown origin) assessed as resistance factor by measuring [GI50(resistant cell line without or with compound)/ GI50(sensitive cell line)] at 10 uM incubated for 72 hrs by MTT assay (Rvb = 7 No_unit)
Format: BAO_0000219
Organism: Homo sapiens
Target: Multidrug resistance-associated protein 1(ALA3004)
Document: ALA4350954
Reversal of ABCC1 (unknown origin)-mediated multidrug resistance in MDCK2 cells co-expressing MRP1 (unknown origin) assessed as resistance factor by measuring [GI50(resistant cell line without or with compound)/ GI50(sensitive cell line)] at 10 uM incubated for 72 hrs by MTT assay (Rvb = 7 No_unit): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4351181
RatioGI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 498.66 | 4.23 | 4.23 |