Basic Information
ID: ALA4351187
Type: Binding
Description: Inhibition of ABCG2 (unknown origin) expressed in MDCK2 cells co-expressing BCRP (unknown origin) assessed as effect on pheophorbide A accumulation pre-incubated for 20 mins followed by pheophorbide A addition and measured after 120 mins by flow cytometric analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: ATP-binding cassette sub-family G member 2(ALA5393)
Document: ALA4350954
Inhibition of ABCG2 (unknown origin) expressed in MDCK2 cells co-expressing BCRP (unknown origin) assessed as effect on pheophorbide A accumulation pre-incubated for 20 mins followed by pheophorbide A addition and measured after 120 mins by flow cytometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4351187
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 469.58 | 3.64 | 3.64 |
| 461.51 | 3.61 | 3.61 |
| 462.56 | 3.82 | 3.82 |
| 419.51 | 3.44 | 3.44 |
| 454.53 | 3.25 | 3.25 |
| 423.97 | 4.83 | 4.83 |
| 498.66 | 4.23 | 4.23 |
| 494.64 | 5.20 | 5.20 |
| 397.48 | 4.00 | 4.00 |
| 414.53 | 4.32 | 4.32 |
| 417.46 | 3.38 | 3.38 |