Basic Information
ID: ALA4351190
Type: Binding
Description: Reversal of ABCB1-mediated multidrug resistance in human A2780/ADR cells assessed as potentiation of daunorubicin-induced cytotoxicity by measuring daunorubicin GI50 at 5 uM incubated for 72 hrs by MTT assay (Rvb = 0.710 +/- 0.034 uM)
Format: BAO_0000219
Organism: Homo sapiens
Target: P-glycoprotein 1(ALA4302)
Document: ALA4350954
Reversal of ABCB1-mediated multidrug resistance in human A2780/ADR cells assessed as potentiation of daunorubicin-induced cytotoxicity by measuring daunorubicin GI50 at 5 uM incubated for 72 hrs by MTT assay (Rvb = 0.710 +/- 0.034 uM): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4351190
GI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 498.66 | 4.23 | 4.23 |