Basic Information
ID: ALA4351197
Type: Binding
Description: Reversal of ABCB1 (unknown origin)-mediated multidrug resistance in MDCK2 cells co-expressing MDR1 (unknown origin) assessed as potentiation of daunorubicin-induced cytotoxicity by measuring daunorubicin GI50 at 1 uM incubated for 72 hrs by MTT assay (Rvb = 7.01 +/- 0.71 uM)
Format: BAO_0000219
Organism: Homo sapiens
Target: P-glycoprotein 1(ALA4302)
Document: ALA4350954
Reversal of ABCB1 (unknown origin)-mediated multidrug resistance in MDCK2 cells co-expressing MDR1 (unknown origin) assessed as potentiation of daunorubicin-induced cytotoxicity by measuring daunorubicin GI50 at 1 uM incubated for 72 hrs by MTT assay (Rvb = 7.01 +/- 0.71 uM): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4351197
GI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 498.66 | 4.23 | 4.23 |