Basic Information
ID: ALA4351249
Type: Binding
Description: Inhibition of [3H]MK0591 binding to human FLAP expressed in human COS7 cell membranes measured after 60 to 80 mins by scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4351249
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.45 | 4.04 | 4.04 |
| 430.51 | 3.91 | 3.91 |
| 452.49 | 2.98 | 2.98 |
| 405.50 | 4.05 | 4.05 |
| 434.50 | 2.85 | 2.85 |
| 405.50 | 3.77 | 3.77 |
| 441.48 | 4.68 | 4.68 |
| 435.50 | 4.13 | 4.13 |
| 445.45 | 4.46 | 4.46 |
| 457.46 | 4.31 | 4.31 |
| 490.56 | 3.00 | 3.00 |
| 392.46 | 4.31 | 4.31 |
| 447.50 | 3.27 | 3.27 |
| 402.50 | 3.82 | 3.82 |
| 391.48 | 3.75 | 3.75 |
| 392.46 | 3.14 | 3.14 |
| 444.53 | 5.79 | 5.79 |
| 390.49 | 4.35 | 4.35 |
| 457.46 | 4.31 | 4.31 |
| 405.46 | 3.50 | 3.50 |
| 405.50 | 4.05 | 4.05 |
| 414.47 | 3.75 | 3.75 |
| 445.45 | 4.46 | 4.46 |
| 402.50 | 4.42 | 4.42 |
| 409.47 | 3.89 | 3.89 |
| 391.48 | 3.75 | 3.75 |
| 416.49 | 3.62 | 3.62 |
| 459.51 | 3.13 | 3.13 |
| 405.50 | 3.76 | 3.76 |
| 405.50 | 4.05 | 4.05 |
| 431.56 | 3.01 | 3.01 |