Basic Information
ID: ALA4351251
Type: Binding
Description: Inhibition of FLAP in human whole blood assessed as reduction in calcium ionophore-stimulated LTB4 production preincubated for 30 mins followed by calcium ionophore stimulation and measured after 20 mins by EIA
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4351251
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.45 | 4.04 | 4.04 |
| 430.51 | 3.91 | 3.91 |
| 452.49 | 2.98 | 2.98 |
| 405.50 | 4.05 | 4.05 |
| 434.50 | 2.85 | 2.85 |
| 405.50 | 3.77 | 3.77 |
| 441.48 | 4.68 | 4.68 |
| 435.50 | 4.13 | 4.13 |
| 445.45 | 4.46 | 4.46 |
| 457.46 | 4.31 | 4.31 |
| 392.46 | 4.31 | 4.31 |
| 402.50 | 3.82 | 3.82 |
| 391.48 | 3.75 | 3.75 |
| 392.46 | 3.14 | 3.14 |
| 444.53 | 5.79 | 5.79 |
| 390.49 | 4.35 | 4.35 |
| 457.46 | 4.31 | 4.31 |
| 405.46 | 3.50 | 3.50 |
| 405.50 | 4.05 | 4.05 |
| 414.47 | 3.75 | 3.75 |
| 445.45 | 4.46 | 4.46 |
| 402.50 | 4.42 | 4.42 |
| 409.47 | 3.89 | 3.89 |
| 391.48 | 3.75 | 3.75 |
| 416.49 | 3.62 | 3.62 |
| 405.50 | 3.76 | 3.76 |
| 405.50 | 4.05 | 4.05 |