Basic Information
ID: ALA4351254
Type: ADME
Description: Inhibition of recombinant human CYP3A4 expressed in Escherichia coli assessed as maximum reduction in metabolite formation using coumarin based substrate by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4351254
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.49 | 2.98 | 2.98 |
| 445.45 | 4.46 | 4.46 |
| 457.46 | 4.31 | 4.31 |
| 392.46 | 4.31 | 4.31 |
| 459.51 | 3.13 | 3.13 |