Basic Information
ID: ALA4351262
Type: ADME
Description: Drug metabolism in cryopreserved human hepatocytes assessed as CYP3A4-mediated fraction metabolized with and without ketoconazole at 1 uM measured up to 180 mins relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4351262
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.49 | 2.98 | 2.98 |
| 434.50 | 2.85 | 2.85 |
| 445.45 | 4.46 | 4.46 |
| 457.46 | 4.31 | 4.31 |
| 490.56 | 3.00 | 3.00 |
| 392.46 | 4.31 | 4.31 |
| 447.50 | 3.27 | 3.27 |
| 457.46 | 4.31 | 4.31 |
| 405.46 | 3.50 | 3.50 |
| 405.50 | 4.05 | 4.05 |
| 414.47 | 3.75 | 3.75 |
| 445.45 | 4.46 | 4.46 |
| 409.47 | 3.89 | 3.89 |
| 391.48 | 3.75 | 3.75 |
| 416.49 | 3.62 | 3.62 |
| 459.51 | 3.13 | 3.13 |