Basic Information
ID: ALA4351510
Type: ADME
Description: Efflux ratio of permeability across apical to basolateral side over basolateral to apical side in MDCK-MDR1 cells at 2 uM
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: MDCK-MDR1
Target: ADMET(ALA612558)
Document: ALA4350959
Efflux ratio of permeability across apical to basolateral side over basolateral to apical side in MDCK-MDR1 cells at 2 uM: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4351510
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.50 | 4.12 | 4.12 |
| 452.51 | 4.26 | 4.26 |
| 456.96 | 4.64 | 4.64 |
| 410.47 | 4.11 | 4.11 |
| 396.45 | 3.72 | 3.72 |
| 426.47 | 3.73 | 3.73 |
| 454.53 | 4.51 | 4.51 |
| 428.46 | 4.25 | 4.25 |
| 468.51 | 3.50 | 3.50 |
| 242.26 | 2.65 | 2.65 |
| 387.42 | 3.90 | 3.90 |
| 373.39 | 4.20 | 4.20 |
| 319.34 | 3.71 | 3.71 |
| 412.45 | 3.40 | 3.40 |
| 286.31 | 3.05 | 3.05 |
| 444.92 | 4.77 | 4.77 |
| 347.40 | 4.58 | 4.58 |
| 375.41 | 3.68 | 3.68 |
| 369.40 | 2.82 | 2.82 |
| 410.47 | 3.95 | 3.95 |
| 375.41 | 3.68 | 3.68 |
| 410.47 | 4.11 | 4.11 |
| 426.47 | 4.24 | 4.24 |
| 349.37 | 3.63 | 3.63 |
| 361.34 | 3.11 | 3.11 |
| 349.37 | 4.15 | 4.15 |
| 374.38 | 4.27 | 4.27 |
| 333.37 | 4.02 | 4.02 |
| 411.46 | 3.51 | 3.51 |
| 387.42 | 3.90 | 3.90 |
| 409.49 | 4.72 | 4.72 |
| 360.35 | 3.71 | 3.71 |
| 372.36 | 4.03 | 4.03 |
| 255.28 | 1.92 | 1.92 |
| 393.40 | 3.82 | 3.82 |
| 389.43 | 4.02 | 4.02 |
| 409.49 | 4.56 | 4.56 |
| 417.44 | 3.91 | 3.91 |
| 447.52 | 3.85 | 3.85 |
| 268.32 | 2.91 | 2.91 |
| 345.38 | 4.34 | 4.34 |
| 373.39 | 4.20 | 4.20 |
| 322.35 | 3.05 | 3.05 |
| 409.47 | 3.49 | 3.49 |
| 317.35 | 3.70 | 3.70 |
| 454.53 | 4.51 | 4.51 |