Basic Information
ID: ALA4351517
Type: Binding
Description: Positive allosteric modulation of human GABAA alpha5beta2gamma2 expressed in HEK293 cells assessed as increase in GABA-stimulated chloride current response at 100 times Ki measured after 15 secs by QPatch electrophysiology method relative to GABA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: GABA-A receptor; alpha-3/beta-3/gamma-2(ALA2094120)
Document: ALA4350959
Positive allosteric modulation of human GABAA alpha5beta2gamma2 expressed in HEK293 cells assessed as increase in GABA-stimulated chloride current response at 100 times Ki measured after 15 secs by QPatch electrophysiology method relative to GABA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4351517
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.50 | 4.12 | 4.12 |
| 417.44 | 3.91 | 3.91 |