Positive allosteric modulation of rat GABAA alpha1beta3gamma2 receptor expressed in CHO cells assessed as increase in GABA-stimulated chloride current...

Basic Information

ID: ALA4351521

Type: Binding

Description: Positive allosteric modulation of rat GABAA alpha1beta3gamma2 receptor expressed in CHO cells assessed as increase in GABA-stimulated chloride current response at 100 times Ki measured after 15 secs by QPatch electrophysiology method relative to GABA

Format: BAO_0000219

Organism: Rattus norvegicus

Cell type: CHO

Target:  Unchecked(ALA612545)

Document:  ALA4350959

Positive allosteric modulation of rat GABAA alpha1beta3gamma2 receptor expressed in CHO cells assessed as increase in GABA-stimulated chloride current response at 100 times Ki measured after 15 secs by QPatch electrophysiology method relative to GABA: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
440.504.124.12
417.443.913.91