Inhibition of human GST/His-tagged RIP1 (1 to 375 residues) expressed in baculovirus expression system assessed as reduction in autophosphorylation me...

Basic Information

ID: ALA4352156

Type: Binding

Description: Inhibition of human GST/His-tagged RIP1 (1 to 375 residues) expressed in baculovirus expression system assessed as reduction in autophosphorylation measured after 4 hrs in presence of ATP by ADP-Glo luminescence assay

Format: BAO_0000019

Organism: Homo sapiens

Target: Receptor-interacting serine/threonine-protein kinase 1(ALA5464)

Document: ALA4350963

Inhibition of human GST/His-tagged RIP1 (1 to 375 residues) expressed in baculovirus expression system assessed as reduction in autophosphorylation measured after 4 hrs in presence of ATP by ADP-Glo luminescence assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4352156

IC50

Total(60)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
228.29	2.75	2.75
244.34	3.30	3.30
308.40	2.40	2.40
245.33	1.93	1.93
221.26	1.98	1.98
230.31	2.99	2.99
335.41	2.65	2.65
231.30	2.39	2.39
220.28	1.72	1.72
230.31	2.99	2.99
220.28	1.72	1.72
231.30	2.39	2.39
367.49	3.76	3.76
396.40	2.80	2.80
246.31	1.96	1.96
251.29	2.65	2.65
251.37	1.96	1.96
334.42	3.26	3.26
339.40	2.55	2.55
335.41	2.65	2.65
242.32	3.14	3.14
353.34	2.75	2.75
352.40	1.62	1.62
222.33	2.81	2.81
256.35	3.53	3.53
238.33	2.05	2.05
258.32	2.37	2.37
299.37	2.20	2.20
244.29	1.98	1.98
262.33	3.44	3.44
396.40	2.80	2.80
216.28	2.60	2.60
251.29	2.65	2.65
230.31	2.99	2.99
351.41	2.22	2.22
313.40	2.59	2.59
271.36	2.29	2.29
286.42	4.29	4.29
248.30	3.13	3.13
396.40	2.80	2.80
231.30	2.39	2.39
375.38	2.83	2.83
362.43	2.89	2.89
352.39	2.49	2.49
368.46	2.95	2.95
299.37	2.20	2.20
251.29	2.65	2.65
264.76	3.65	3.65
335.41	2.65	2.65
396.40	2.80	2.80
250.30	3.26	3.26
333.44	3.86	3.86
362.43	2.89	2.89
264.76	3.65	3.65
351.41	2.22	2.22
352.39	2.49	2.49
361.45	3.50	3.50
236.36	3.20	3.20
266.29	3.27	3.27
333.44	3.86	3.86