Basic Information
ID: ALA4352642
Type: Binding
Description: Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells at 1 uM using PIP2 as substrate measured after 80 mins by transcreener fluorescence polarization assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: PI3-kinase p110-delta/p85-alpha(ALA2111432)
Document: ALA4350965
Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells at 1 uM using PIP2 as substrate measured after 80 mins by transcreener fluorescence polarization assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4352642
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.43 | 3.75 | 3.75 |
| 416.87 | 4.48 | 4.48 |
| 432.88 | 3.15 | 3.15 |
| 398.43 | 2.49 | 2.49 |
| 473.92 | 3.95 | 3.95 |
| 416.42 | 2.63 | 2.63 |
| 461.91 | 3.05 | 3.05 |
| 457.47 | 3.44 | 3.44 |
| 471.93 | 1.87 | 1.87 |
| 474.89 | 3.57 | 3.57 |
| 456.90 | 3.62 | 3.62 |
| 491.91 | 3.90 | 3.90 |
| 491.91 | 4.09 | 4.09 |
| 422.45 | 2.97 | 2.97 |
| 450.87 | 3.09 | 3.09 |
| 432.88 | 2.72 | 2.72 |
| 450.87 | 3.29 | 3.29 |