Basic Information
ID: ALA4352645
Type: Binding
Description: Inhibition of PI3Kgamma in rat RAW264.7 cells assessed as reduction in C5a-stimulated AKT phosphorylation at Ser473 residue preincubated for 30 mins followed by C5a-stimulation and measured after 5 mins
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: RAW264.7
Target: Unchecked(ALA612545)
Document: ALA4350965
Inhibition of PI3Kgamma in rat RAW264.7 cells assessed as reduction in C5a-stimulated AKT phosphorylation at Ser473 residue preincubated for 30 mins followed by C5a-stimulation and measured after 5 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4352645
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.43 | 3.75 | 3.75 |
| 416.87 | 4.48 | 4.48 |
| 432.88 | 3.15 | 3.15 |
| 418.85 | 2.76 | 2.76 |
| 398.43 | 2.49 | 2.49 |
| 442.87 | 3.23 | 3.23 |
| 473.92 | 3.95 | 3.95 |
| 416.42 | 2.63 | 2.63 |
| 457.47 | 3.44 | 3.44 |
| 418.85 | 2.33 | 2.33 |
| 459.90 | 3.56 | 3.56 |
| 474.89 | 3.57 | 3.57 |
| 456.90 | 3.62 | 3.62 |
| 491.91 | 3.90 | 3.90 |
| 491.91 | 4.09 | 4.09 |
| 422.45 | 2.97 | 2.97 |
| 450.87 | 3.09 | 3.09 |
| 432.88 | 2.72 | 2.72 |
| 450.87 | 3.29 | 3.29 |