Basic Information
ID: ALA4352652
Type: Binding
Description: Inhibition of PI3Kdelta in rat whole blood assessed as reduction in anti-IgD-stimulated CD86 expression on B-cells preincubated for 60 mins followed by anti-IgD stimulation and measured after overnight incubation by flow cytometry
Format: BAO_0000221
Organism: Rattus norvegicus
Tissue: Blood
Target: Unchecked(ALA612545)
Document: ALA4350965
Inhibition of PI3Kdelta in rat whole blood assessed as reduction in anti-IgD-stimulated CD86 expression on B-cells preincubated for 60 mins followed by anti-IgD stimulation and measured after overnight incubation by flow cytometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4352652
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.87 | 4.48 | 4.48 |
| 435.88 | 2.66 | 2.66 |