Basic Information
ID: ALA4352686
Type: Binding
Description: Positive allosteric modulation of human CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced beta-arrestin recruitment at 1000 nM preincubated for 30 mins followed by CP55940 addition and measured after 90 to 180 mins by PathHunter assay relative to CP55940
Format: BAO_0000219
Organism: Homo sapiens
Target: Cannabinoid CB1 receptor(ALA218)
Document: ALA4350967
Positive allosteric modulation of human CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced beta-arrestin recruitment at 1000 nM preincubated for 30 mins followed by CP55940 addition and measured after 90 to 180 mins by PathHunter assay relative to CP55940: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4352686
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 326.42 | 4.82 | 4.82 |
| 369.39 | 6.82 | 6.82 |
| 367.48 | 6.00 | 6.00 |
| 336.44 | 6.19 | 6.19 |
| 362.45 | 5.61 | 5.61 |
| 356.86 | 6.53 | 6.53 |
| 365.40 | 6.92 | 6.92 |
| 373.44 | 5.18 | 5.18 |
| 354.48 | 5.60 | 5.60 |
| 361.45 | 5.94 | 5.94 |
| 357.42 | 6.98 | 6.98 |