Basic Information
ID: ALA4352689
Type: Binding
Description: Positive allosteric modulation of human CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced beta-arrestin recruitment at 1 uM preincubated for 30 mins followed by CP55940 addition and measured after 90 to 180 mins by PathHunter assay relative to CP55940
Format: BAO_0000219
Organism: Homo sapiens
Target: Cannabinoid CB1 receptor(ALA218)
Document: ALA4350967
Positive allosteric modulation of human CB1 receptor expressed in CHOK1 cells assessed as increase in CP55940-induced beta-arrestin recruitment at 1 uM preincubated for 30 mins followed by CP55940 addition and measured after 90 to 180 mins by PathHunter assay relative to CP55940: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4352689
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.43 | 7.23 | 7.23 |
| 380.44 | 5.75 | 5.75 |
| 322.41 | 5.88 | 5.88 |
| 426.88 | 5.66 | 5.66 |
| 425.94 | 6.02 | 6.02 |
| 424.91 | 6.16 | 6.16 |
| 385.45 | 7.29 | 7.29 |
| 358.36 | 5.14 | 5.14 |
| 440.91 | 5.75 | 5.75 |
| 412.90 | 5.97 | 5.97 |
| 379.49 | 5.56 | 5.56 |
| 341.41 | 5.44 | 5.44 |
| 407.88 | 5.83 | 5.83 |
| 401.45 | 6.47 | 6.47 |
| 365.40 | 6.92 | 6.92 |
| 381.87 | 6.28 | 6.28 |
| 396.90 | 6.27 | 6.27 |
| 407.88 | 5.83 | 5.83 |
| 360.38 | 5.39 | 5.39 |
| 313.40 | 4.96 | 4.96 |
| 393.42 | 5.21 | 5.21 |
| 381.40 | 5.89 | 5.89 |
| 417.32 | 6.61 | 6.61 |
| 400.86 | 6.10 | 6.10 |
| 386.44 | 6.56 | 6.56 |
| 412.90 | 5.97 | 5.97 |
| 428.48 | 6.94 | 6.94 |
| 347.42 | 5.63 | 5.63 |
| 460.96 | 5.36 | 5.36 |
| 373.44 | 5.18 | 5.18 |
| 464.53 | 6.35 | 6.35 |
| 379.38 | 6.10 | 6.10 |
| 368.50 | 5.99 | 5.99 |
| 415.44 | 6.68 | 6.68 |