Basic Information
ID: ALA4352728
Type: Binding
Description: Inhibition of Plasmodium falciparum N-terminal His6-tagged falcipain-2 (35 residues) expressed in Escherichia coli M15 pREP4 using Z-Lue-Arg-AMC as substrate measured after 30 mins by spectrofluorometric method
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA4352728
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.88 | 4.81 | 4.81 |
| 282.34 | 2.39 | 2.39 |
| 357.41 | -1.46 | -1.46 |
| 804.91 | 3.44 | 3.44 |
| 846.99 | 4.61 | 4.61 |
| 897.05 | 5.30 | 5.30 |
| 875.04 | 5.25 | 5.25 |
| 854.97 | 4.27 | 4.27 |
| 889.07 | 5.64 | 5.64 |
| 844.97 | 4.37 | 4.37 |
| 846.99 | 4.61 | 4.61 |
| 854.97 | 4.27 | 4.27 |
| 887.05 | 5.54 | 5.54 |
| 915.11 | 6.17 | 6.17 |
| 844.97 | 4.37 | 4.37 |
| 820.95 | 4.08 | 4.08 |
| 885.04 | 5.29 | 5.29 |
| 778.87 | 3.05 | 3.05 |
| 840.94 | 3.88 | 3.88 |
| 895.03 | 5.20 | 5.20 |