Assay Report Card

Basic Information

ID: ALA4352739

Type: ADME

Description: Drug metabolism in mouse liver microsomes assessed as N,N-bis-demethylation at 10 uM measured after 60 mins in presence of NADPH-generating system by UPLC-MS analysis

Organism: Mus musculus

Tissue: Liver

Subcellular Fraction: Microsome

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
897.055.305.30
875.045.255.25
854.974.274.27