Basic Information
ID: ALA4352755
Type: Binding
Description: Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopic analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Serine-protein kinase ATR(ALA5024)
Document: ALA4350970
Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopic analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4352755
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.47 | 3.16 | 3.16 |
| 422.51 | 3.77 | 3.77 |
| 420.50 | 3.16 | 3.16 |
| 463.56 | 3.95 | 3.95 |
| 437.55 | 4.09 | 4.09 |
| 420.49 | 4.23 | 4.23 |
| 449.54 | 3.69 | 3.69 |
| 533.65 | 4.50 | 4.50 |
| 421.48 | 3.62 | 3.62 |
| 498.01 | 4.60 | 4.60 |
| 421.48 | 3.62 | 3.62 |
| 463.56 | 4.25 | 4.25 |
| 420.49 | 4.23 | 4.23 |
| 477.59 | 4.34 | 4.34 |
| 498.01 | 4.60 | 4.60 |
| 420.49 | 4.23 | 4.23 |
| 463.56 | 4.25 | 4.25 |
| 421.48 | 3.62 | 3.62 |