Basic Information
ID: ALA4352822
Type: Binding
Description: Inhibition of mTORC1 in human RD cells assessed as reduction in P70S6K1 phosphorylation at Thr 389 site at 20 uM incubated for 2 hrs in presence of insulin by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: RD
Target: mTORC1(ALA4296661)
Document: ALA4350972
Inhibition of mTORC1 in human RD cells assessed as reduction in P70S6K1 phosphorylation at Thr 389 site at 20 uM incubated for 2 hrs in presence of insulin by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4352822
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 914.19 | 6.18 | 6.18 |
| 447.46 | 6.85 | 6.85 |
| 502.50 | 5.46 | 5.46 |
| 428.37 | 3.83 | 3.83 |
| 421.38 | 5.52 | 5.52 |
| 447.42 | 5.63 | 5.63 |
| 446.43 | 5.88 | 5.88 |
| 552.51 | 7.23 | 7.23 |
| 550.54 | 6.80 | 6.80 |
| 515.54 | 5.37 | 5.37 |
| 532.52 | 6.97 | 6.97 |
| 502.50 | 6.21 | 6.21 |
| 566.54 | 7.37 | 7.37 |
| 460.46 | 5.69 | 5.69 |
| 488.47 | 5.97 | 5.97 |
| 486.50 | 6.22 | 6.22 |
| 471.44 | 5.72 | 5.72 |
| 502.50 | 6.36 | 6.36 |
| 435.38 | 5.76 | 5.76 |
| 435.38 | 5.76 | 5.76 |
| 516.52 | 6.75 | 6.75 |
| 447.42 | 5.28 | 5.28 |