Basic Information
ID: ALA4353031
Type: Functional
Description: Antitrypanosomal activity against Trypanosoma cruzi amastigotes infected in BALB/c mouse peritoneal macrophages assessed as decrease in parasitic load with in the cell incubated for 48 hrs by Giemsa staining based light microscopy
Organism: Trypanosoma cruzi
Activity Charts
Bioactivity
Activity Types for Assay ALA4353031
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 260.25 | 1.11 | 1.11 |
| 326.39 | 4.66 | 4.66 |
| 340.42 | 4.96 | 4.96 |
| 420.55 | 6.98 | 6.98 |
| 386.53 | 6.58 | 6.58 |
| 330.42 | 5.11 | 5.11 |
| 358.48 | 5.80 | 5.80 |
| 326.39 | 5.27 | 5.27 |
| 386.49 | 5.72 | 5.72 |
| 372.51 | 6.19 | 6.19 |
| 372.46 | 5.33 | 5.33 |
| 316.31 | 3.13 | 3.13 |
| 340.42 | 5.57 | 5.57 |
| 376.45 | 3.35 | 3.35 |
| 366.46 | 5.52 | 5.52 |
| 416.52 | 6.53 | 6.53 |
| 368.43 | 4.88 | 4.88 |
| 344.45 | 5.41 | 5.41 |
| 354.45 | 5.35 | 5.35 |
| 362.42 | 3.05 | 3.05 |
| 370.49 | 5.97 | 5.97 |
| 382.50 | 6.13 | 6.13 |
| 382.46 | 5.27 | 5.27 |
| 372.42 | 3.77 | 3.77 |
| 368.47 | 5.74 | 5.74 |
| 376.45 | 4.39 | 4.39 |