Basic Information
ID: ALA4353043
Type: Binding
Description: Inhibition of dengue virus serotype 2 His-tagged NS2B cofactor domain-NS3 protease expressed in Escherichia coli at 50 uM using 2-Abz-Nle-Lys-Arg-Arg-Ser-(3-NO2)-Tyr-NH2 as substrate preincubated with enzyme for 15 mins followed by substrate addition measured for every 1 sec for 15 mins by fluorescence plate reader based HPLC analysis relative to control
Organism: dengue virus type 2
Activity Charts
Bioactivity
Activity Types for Assay ALA4353043
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 311.35 | 1.55 | 1.55 |
| 398.42 | 1.39 | 1.39 |
| 312.33 | 1.52 | 1.52 |
| 285.31 | 2.19 | 2.19 |
| 292.34 | 0.41 | 0.41 |
| 270.29 | 1.79 | 1.79 |
| 278.32 | 0.02 | 0.02 |
| 312.33 | 1.52 | 1.52 |
| 311.35 | 1.55 | 1.55 |
| 278.32 | 0.16 | 0.16 |
| 292.34 | 0.55 | 0.55 |
| 284.32 | 1.67 | 1.67 |
| 270.29 | 1.79 | 1.79 |