Assay Report Card

Basic Information

ID: ALA4353044

Type: Binding

Description: Inhibition of West Nile virus His-tagged NS2B cofactor domain-NS3 protease expressed in Escherichia coli at 50 uM using 2-Abz-Gly-Leu-Lys-Arg-Gly-Gly-(3-NO2)-Tyr-NH2 as substrate preincubated with enzyme for 15 mins followed by substrate addition measured for every 1 sec for 15 mins by fluorescence microplate reader based HPLC analysis relative to control

Organism: West Nile virus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
311.351.551.55
398.421.391.39
312.331.521.52
285.312.192.19
292.340.410.41
270.291.791.79
278.320.020.02
312.331.521.52
311.351.551.55
278.320.160.16
292.340.550.55
284.321.671.67
270.291.791.79