Basic Information
ID: ALA4353050
Type: Binding
Description: Time-dependent inhibition of dengue virus serotype 2 His-tagged NS2B cofactor domain-NS3 protease expressed in Escherichia coli at 50 uM using 2-Abz-Nle-Lys-Arg-Arg-Ser-(3-NO2)-Tyr-NH2 as substrate preincubated with enzyme for 20 to 40 mins followed by substrate addition measured for every 1 sec for 15 mins by fluorescence plate reader based HPLC analysis
Format: BAO_0000019
Organism: dengue virus type 2
Target: Dengue virus type 2 NS3 protein(ALA5980)
Document: ALA4350980
Time-dependent inhibition of dengue virus serotype 2 His-tagged NS2B cofactor domain-NS3 protease expressed in Escherichia coli at 50 uM using 2-Abz-Nle-Lys-Arg-Arg-Ser-(3-NO2)-Tyr-NH2 as substrate preincubated with enzyme for 20 to 40 mins followed by substrate addition measured for every 1 sec for 15 mins by fluorescence plate reader based HPLC analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4353050
TDI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 311.35 | 1.55 | 1.55 |
| 312.33 | 1.52 | 1.52 |
| 284.32 | 1.67 | 1.67 |
| 270.29 | 1.79 | 1.79 |