Basic Information
ID: ALA4353060
Type: Binding
Description: Inhibition of dengue virus serotype 2 His-tagged NS2B cofactor domain-NS3 protease expressed in Escherichia coli at 1 mM using 2-Abz-Nle-Lys-Arg-Arg-Ser-(3-NO2)-Tyr-NH2 as substrate preincubated with enzyme for 15 mins followed by substrate addition measured for every 1 sec for 15 mins by fluorescence plate reader based HPLC analysis relative to control
Format: BAO_0000019
Organism: dengue virus type 2
Target: Dengue virus type 2 NS3 protein(ALA5980)
Document: ALA4350980
Inhibition of dengue virus serotype 2 His-tagged NS2B cofactor domain-NS3 protease expressed in Escherichia coli at 1 mM using 2-Abz-Nle-Lys-Arg-Arg-Ser-(3-NO2)-Tyr-NH2 as substrate preincubated with enzyme for 15 mins followed by substrate addition measured for every 1 sec for 15 mins by fluorescence plate reader based HPLC analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4353060
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 285.31 | 2.19 | 2.19 |
| 257.29 | 2.49 | 2.49 |
| 285.35 | 2.24 | 2.24 |
| 299.33 | 1.86 | 1.86 |
| 370.41 | 1.76 | 1.76 |
| 271.32 | 2.36 | 2.36 |
| 370.41 | 1.76 | 1.76 |
| 243.27 | 2.46 | 2.46 |
| 398.43 | 1.61 | 1.61 |