Assay Report Card

Basic Information

ID: ALA4353061

Type: Binding

Description: Inhibition of West Nile virus His-tagged NS2B cofactor domain-NS3 protease expressed in Escherichia coli at 1 mM using 2-Abz-Gly-Leu-Lys-Arg-Gly-Gly-(3-NO2)-Tyr-NH2 as substrate preincubated with enzyme for 15 mins followed by substrate addition measured for every 1 sec for 15 mins by fluorescence microplate reader based HPLC analysis relative to control

Organism: West Nile virus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
285.312.192.19
257.292.492.49
285.352.242.24
299.331.861.86
370.411.761.76
271.322.362.36
370.411.761.76
243.272.462.46
398.431.611.61