Basic Information
ID: ALA4353138
Type: Binding
Description: Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Tyrosine-protein kinase receptor FLT3(ALA1974)
Document: ALA4350983
Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4353138
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.83 | 5.55 | 5.55 |
| 394.46 | 2.80 | 2.80 |
| 369.49 | 3.64 | 3.64 |
| 435.53 | 3.85 | 3.85 |
| 455.47 | 4.16 | 4.16 |
| 494.06 | 5.89 | 5.89 |
| 424.53 | 3.88 | 3.88 |
| 419.49 | 3.56 | 3.56 |
| 364.48 | 3.51 | 3.51 |
| 391.43 | 2.47 | 2.47 |
| 394.46 | 2.80 | 2.80 |
| 373.91 | 4.29 | 4.29 |
| 419.49 | 3.20 | 3.20 |
| 382.49 | 2.73 | 2.73 |
| 424.51 | 3.91 | 3.91 |
| 433.51 | 3.61 | 3.61 |
| 420.54 | 4.08 | 4.08 |
| 417.51 | 3.77 | 3.77 |
| 406.52 | 3.77 | 3.77 |
| 339.47 | 3.63 | 3.63 |
| 408.49 | 3.24 | 3.24 |
| 366.45 | 3.17 | 3.17 |
| 418.36 | 4.40 | 4.40 |
| 456.53 | 2.09 | 2.09 |
| 424.53 | 3.00 | 3.00 |
| 442.55 | 3.10 | 3.10 |
| 369.49 | 3.64 | 3.64 |
| 407.50 | 3.16 | 3.16 |
| 366.45 | 3.17 | 3.17 |
| 405.46 | 2.81 | 2.81 |
| 500.51 | 6.13 | 6.13 |
| 508.49 | 5.99 | 5.99 |
| 532.04 | 6.90 | 6.90 |
| 431.57 | 5.05 | 5.05 |
| 373.91 | 4.29 | 4.29 |
| 418.36 | 4.40 | 4.40 |
| 392.42 | 2.89 | 2.89 |
| 364.48 | 3.51 | 3.51 |
| 412.48 | 2.03 | 2.03 |
| 384.47 | 2.39 | 2.39 |
| 440.96 | 4.42 | 4.42 |
| 438.51 | 2.87 | 2.87 |